Bacterial infections are infectious diseases caused by bacteria, which live on and in many different organs, including the human body. Bacteria differ in their causes, mechanisms of transmission, and time frames. The earliest known bacterial agents of disease are gram-positive and gram-negative bacilli, which are members of the phylum Eubacteria. Other bacteria, such as treponemes and chlamydiae, can also cause disease.

These organisms often multiply outside the host. Indirect infections occur when an individual comes into contact with an organism that has been contaminated by another person. While these organisms are everywhere, they are more likely to be transmitted from one person to another through the use of personal care products. Other methods of indirect transmission involve consuming contaminated food or water. Fecal-oral contact, for example, occurs when sewage water is used to wash food. This type of infection is common in developing countries with poorly functioning sewage systems.

Many of the bacteria responsible for bacterial infections are resistant to antibiotics, making them increasingly difficult to treat. The WHO has created a list of the most dangerous and common pathogens to guide the development of new antibiotics. There are three tiers of priority pathogens: high, critical, and low. The high priority group contains multi-drug-resistant bacteria that pose an unusually large threat to the health of hospitals and other healthcare settings.

Generally, bacteria are classified into two groups, Gram-positive and Gram-negative, according to their susceptibility to various antibiotics. Gram-positive bacteria have thick cell walls, which are external to the cell membrane. Gram-negative bacteria have thin cell walls, and therefore do not retain a purple stain. The second stain helps identify Gram-negative bacteria, which have thin cell walls. Under a microscope, these organisms will appear pink or red.

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